Case Studies
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Client: CSL Plasma (Contract via Roth Staffing)
Duration: May 2022 – May 2025Challenge
CSL Plasma, a global leader in plasma collection and biopharmaceutical manufacturing, needed a unified approach to process documentation and communication across its U.S., German, and Hungarian operations. The existing documentation was fragmented, inconsistent, and lacked visibility across regions - resulting in inefficiencies, compliance risks, and limited knowledge-sharing.
Key challenges included:
A decentralized documentation approach with over 1,000 workflows in need of organization and standardization.
Misalignment between Standard Operating Procedures (SOPs), Work Instructions (WIs), and actual workflows.
The need for bilingual (German/English) documentation to support cross-regional teams.
Limited staff training and adoption of ARIS BPM, the organization’s process documentation platform.
Approach
1. Foundation – Building a Central Repository
Managed CSL Plasma’s global ARIS-based process repository, consolidating over 1,000 workflows into a standardized framework.
Conducted gap analyses by reviewing existing SOPs, WIs, and workflows to identify redundancies and compliance risks.
Established best practices for multilingual documentation to ensure consistency in German/English translations.
2. Enablement – Improving Processes & Engagement
Partnered with 20+ subject matter experts (SMEs) and cross-functional stakeholders to redesign outdated workflows and integrate newly developed lab and center procedures.
Created and reworked bilingual process flows, narratives, and digital content to enhance compliance, operational efficiency, and staff engagement.
Ensured alignment between SOPs/WIs and workflow documentation to close gaps and strengthen quality assurance.
3. Growth – Training & Adoption for Long-Term Success
Delivered targeted ARIS BPM training sessions for plasma center staff, enabling teams to independently manage and update documentation.
Increased adoption of the ARIS platform by demonstrating its value as a centralized, global knowledge repository.
Set the foundation for long-term quality improvement by embedding process visibility and alignment across all three regions.
Results
Streamlined operations: Over 1,000 workflows standardized, improving cross-regional efficiency and reducing documentation gaps.
Compliance improvement: Alignment between workflows, SOPs, and WIs strengthened regulatory readiness and audit preparedness.
Bilingual integration: Consistent English/German documentation improved accessibility and collaboration for international teams.
Knowledge adoption: ARIS BPM training empowered staff to maintain and update documentation, fostering a culture of self-sufficiency.
Global alignment: Enhanced communication and visibility across Germany, Hungary, and the U.S. created a unified framework for process improvement.
Impact Statement
By leading CSL Plasma’s global process communication strategy, a scalable documentation system was delivered that not only improved operational efficiency but also reinforced compliance and quality in plasma center and lab operations worldwide.